Research progress of GLP-2 in non-alcoholic fatty liver disease

Corresponding author: ZHANG Shujuan, suanju21@163.com

DOI: 10.12201/bmr.202502.00018

•  

  Abstract: Nonalcoholic Fatty Liver Disease (NAFLD) is an increasingly common chronic liver disease worldwide. It has become the most common chronic liver disease in adults and children. The incidence of NAFLD is increasing year by year and shows a trend of younger age. The occurrence of NAFLD is closely related to insulin resistance, obesity, type 2 diabetes and other metabolic syndromes. In recent years, glucagon-like peptide-2 (GLP-2), as a hormone specifically expressed in intestinal tissues, has been gradually discovered and paid attention to its role in insulin resistance and lipid metabolism. This article aims to review the research progress of GLP-2 in non-alcoholic fatty liver disease.

  Key words: Glucagon-like peptide-2; non-alcoholic fatty liver disease; Obesity Lipid metabolism; Insulin resistance; 

  Submit time: 13 February 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• NIU Xiao Shan. Advances in pharmacological studies of NF-κB involved in the regulation of nonalcoholic fatty liver disease. 2024. doi: 10.12201/bmr.202410.00006

  JIA Chen, GONG Yan, HAN Yijing, JIANG Jianan, LIU Weizheng, ZHANG Daxu, LU Wenping. Correlation between psychological stress and metabolic-associated fatty liver disease. 2022. doi: 10.12201/bmr.202204.00003

  Ming-Dou Du. Study on the causal relationship between physical activity and insulin sensitivity. 2022. doi: 10.12201/bmr.202210.00027

  张楠, dujing. Research progress of O2O model in chronic disease management. 2024. doi: 10.12201/bmr.202407.00026

  Zhenghaijuan, NiuXiaohan. Research Progress of CCR and metabolic syndrome and its related diseases. 2025. doi: 10.12201/bmr.202501.00048

  TUO Chen-long, ZHANG De-hong, YANG Yang, GU Yu-biao, ZHANG Lei, GUO Jia-jun. Research Advances in P2X Ion Channels in Knee Osteoarthritis. 2025. doi: 10.12201/bmr.202502.00024

  shen pei cheng. Overview of TCM non-drug therapy of chronic kidney disease. 2024. doi: 10.12201/bmr.202409.00054

  HONG Liang, PAN Anna, WU Yanghe, YE Xiaoting. Esculin improve lipid accumulation in hepatocytes by inhibiting the PERK/eIF2A/ATF4 signaling pathway. 2024. doi: 10.12201/bmr.202409.00013

  Zhang Han, Chu Mengyuan, Xu Kaikai, Xiang Xin, Yan Ying. Progress in Mechanism of Action of Isthmin1 Protein in Polycystic Ovary Syndrome. 2024. doi: 10.12201/bmr.202411.00004

  yanglin, yangyang. Research Progress on Autophagy-Dependent Ferroptosis in Cancer. 2024. doi: 10.12201/bmr.202410.00029

• ID	Submit time	Number	Download
  1	2024-12-13	bmr.202502.00018V1	Download

• Public  Anonymous  To author only Submit Comments