Research Progress on the Impact of Hyperuricemia on Chronic Kidney Disease

DOI: 10.12201/bmr.202503.00045

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  Abstract: The incidence of hyperuricemia (HUA) and chronic kidney disease (CKD) has been rising annually, and the association between these two conditions, along with their underlying mechanisms, has garnered significant attention. In recent years, the potential benefits of urate-lowering therapy in the management of CKD have become a subject of controversy. This review focuses on four key aspects: the correlation between HUA and CKD, pathological mechanisms, ongoing debates regarding urate-lowering therapy in CKD management, and future research directions.

  Key words: Hyperuricemia; Chronic Kidney Disease; Pathological Mechanisms; Urate-Lowering Therapy; Research Progress

  Submit time: 14 March 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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