Observation on the Clinical Application of Integrative Medicine in the Management of Non-dialysis Patients with Stage 3-5 Chronic Kidney DiseaseXIE Wenjia,NI Jianing,ZHOU Shuyan,ZHANG Tingting,CAI Xudong

DOI: 10.12201/bmr.202409.00065

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  Abstract: Objective To explore the clinical effect of integrative medicine in the management of non-dialysis patients with stage 3-5 chronic kidney disease.Method 164 cases of non-dialysis patients with stage 3-5 chronic kidney disease treated in the nephrology department of Ningbo Municipal Hospital of Traditional Chinese Medicine from February 2022 to December 2022 were retrospectively collected，and be randomly divided into a control group and a management group，with 82 cases in each group. The control group underwent regular CKD outpatient management，the management group underwent CKD integrative medicine management.Use paired sample t-test to compare the changes in blood uric acid, cholesterol, albumin, and subjective scale scores between two groups of patients before and after follow-up,use independent sample t-test to compare the inter group differences of the above indicators,use chi square test to compare the incidence of hyperkalemia, hyperphosphatemia, anemia, and renal function progression between two groups of patients.During the follow-up period, 3 cases were lost in each group.Result The blood uric acid and cholesterol levels in the management group after 1 year’s follow-up were lower than that before the follow-up,and the blood uric acid in the management group was lower than that in the control group（P＜0.05）;The incidence of hyperkalemia, hyperphosphatemia, anemia, and renal function progression in the management group was lower than that in the control group（P＜0.05）；The KiKS score and SF-36 total score of the management group were higher than those of the control group,and the total score of traditional Chinese medicine syndrome was smaller than that of the control group（P＜0.05）.Conclusion The application of integrative medicine in the management of non-dialysis patients with stage 3-5 has a significant effect,which could effectively reduce risk factors for CKD progression, controlle complications, delay renal function progression,and Improve the quality of life for patients.

  Key words: Integrative medicine; Chronic disease management; Stage 3-5 chronic kidney disease

  Submit time: 29 September 2024

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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