• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

Clinical application of dermatoscope combined with rapid frozen section examination in the treatment of head and face skin tumors.

DOI: 10.12201/bmr.202502.00028
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: Objective To evaluate the application value of dermatoscope combined with quick frozen section examination in the treatment of head and face skin tumors. Methods Retrospective analysis of 123 patients with head and neck skin tumors admitted to the Dermatology Department of Jinhua Municipal Central Hospital from June 2019 to December 2023. They were treated using a combination of skin biopsy and intraoperative rapid frozen section as well as preoperative dermoscopy and intraoperative rapid frozen section assessment.The surgical cure rate of the two methods and the coincidence rate of dermatoscope image diagnosis, quick frozen section diagnosis and paraffin section diagnosis were statistically analyzed and compared.Results There is no significant difference between preoperative dermoscopy combined with intraoperative quick frozen section examination and preoperative skin biopsy combined with intraoperative quick frozen section examination in the treatment of head and face skin tumors. The coincidence rate of dermoscopy image analysis technology and paraffin section diagnosis is 91.36%, and the coincidence rate of quick-frozen section examination diagnosis is 98.37%. All cases reported negative in basal margins by intraoperative quick frozen section and postoperative paraffin section, and no recurrence was found after 6 months follow-up. Conclusion In the surgical treatment of head and face skin tumors, dermoscopy combined with intraoperative rapid frozen section examination has obvious effect, which can replace preoperative skin biopsy and is worthy of clinical promotion.

    Key words: dermatoscope; image analysis; technology,quick; frozen section,pathological; diagnosis,skin; tumor

    Submit time: 17 February 2025

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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    1 2025-01-11

    bmr.202502.00028V1

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ZENG Lei, JIANG Yuan, WANG Meiyan, JIANG Bingjing, ZHANG Yanfei. Clinical application of dermatoscope combined with rapid frozen section examination in the treatment of head and face skin tumors.. 2025. biomedRxiv.202502.00028

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