Exploring the Medication Patterns of Pediatric Night Cough Treatment Based on the Shaoyang Pivot Theory through Data Mining

Corresponding author: WANG Xiaoyan, yzrx66@163.com

DOI: 10.12201/bmr.202502.00014

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  Abstract: Objective To explore the drug use rules of Professor Wang Xiaoyans treatment of pediatric night cough based on the Shaoyang as the axis theory. Methods 189 cases of night cough patients (including 224 prescriptions) were included, and the disease time distribution, syndrome type, and drug four qi five flavors were analyzed using the traditional Chinese medicine inheritance auxiliary platform. Frequency statistics, association rule analysis, and cluster analysis were used to extract the drug use rules. Results The study found: ① The cough time was highest at 3-5 am (41.2%); ② The syndrome type was mainly Shaoyang syndrome (Shaoyang syndrome with phlegm and drink 27.2%, Shaoyang syndrome with food stagnation 23.2%, Shaoyang syndrome with qi deficiency 18.8%, Shaoyang syndrome with yin deficiency 18.3%, Shaoyang syndrome with phlegm and heat 12.5%); ③ The high-frequency core drugs were Chai Hu, Huang Qin, and Ban Xia, etc. 17 flavors, the prescription characteristics were Xiao Chai Hu Tang without Ren Shen, Sheng Jiang, and Da Zao, and added Wu Wei Zi and Dang Gui; ④ The drugs were used flexibly according to the syndromes: Ma Xing Shi Gan Tang was added to the phlegm and drink syndrome, Qi Ju Di Tan Tang was added to the food stagnation syndrome, Si Jun Zi Tang was added to the qi deficiency syndrome, Mai Wei Di Huang Tang was added to the yin deficiency syndrome, and Wei Jing Tang was added to the phlegm and heat syndrome. Conclusion Professor Wangs treatment is based on the basic principle of harmonizing Shaoyang, and according to the disease mechanism, the classical prescription is flexibly used, forming a night cough treatment system based on the Shaoyang as the axis theory, with distinct clinical characteristics.

  Key words: Night cough; Data mining; Shaoyang theory; Experience of renowned doctors; Wang Xiaoyan

  Submit time: 11 February 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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