• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

Clinical effect of She medical diet cool tea compound in treating obesity with excessive phlegm-dampness complicated with OSAHS1

Corresponding author: zhou minhua, 352538912@qq.com
DOI: 10.12201/bmr.202411.00012
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: Objective: To investigate the clinical efficacy and safety of She medical diet cool tea compound in treating obesity with excessive phlegm-dampness complicated with obstructive sleep apnea hypopnea syndrome.Method: From January 1, 2023 to February 29, 2024, 90 obese patients with excessive phlegm-dampness complicated with OSAHS admitted to Lishui Traditional Chinese Medicine Hospital were selected as the research subjects. Through the random number table method, they are randomly divided into control group (45 cases) and treatment group (45 cases); The control group received non-invasive ventilator assisted ventilation in Continuous Positive Airway Pressure mode; The treatment group was treated with She medical diet cool tea compound on the basis of the control group;Both groups were treated for 3 months。 The body mass index, Epworth drowsiness scale score, sleep apnea parameters, and safety were compared between the two groups.Result:After treatment, the ESS score, BMI and Apnea-Hyponea Index (AHI) of the two groups were lower than before treatment, and the minimum blood oxygen saturation (LSa O2) was higher than before treatment, which was statistically significant (P<0.05); and the treatment group ESS score and BMI were lower than the control group (P values 0.034 and 0.019 respectively), and the sleep apnea parameters (AHI, LSA O2) in the treatment group were better than that of the control group (0.000 and 0.025 respectively); During the treatment, both groups of patients had dry mouth, headache, abdominal distension and other adverse reactions. Compared with the control, the treatment group was less (P<0.05).Conclusion:The She medical diet cool tea compound has a definite therapeutic effect on the treatment of obesity with excessive phlegm-dampness complicated with OSAHS. It can reduce body mass index and ESS score, improve sleep apnea parameters, and reduce adverse reactions caused by non-invasive ventilator-associated ventilation.

    Key words: She medical diet cool tea compound; obstructive sleep apnea hypopnea syndrome; Obesity; excessive phlegm-dampness type; Clinical effect and safety; 

    Submit time: 7 November 2024

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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    1 2024-08-16

    bmr.202411.00012V1

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zhou minhua. Clinical effect of She medical diet cool tea compound in treating obesity with excessive phlegm-dampness complicated with OSAHS1. 2024. biomedRxiv.202411.00012

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