The role of minimal RNA in sepsis-related acute kidney injury

DOI: 10.12201/bmr.202410.00011

•  

  Abstract: 【】Sepsis-associated renal injury (Sepsis-associated acute kidney injury, SAKI) is a common complication in acute and critical ill patients. According to the existing criteria for the diagnosis of renal injury in sepsis (KDIGO criteria), most patients are found that the renal damage is irreversible, so it is very important for early diagnosis and treatment to prevent further deterioration of SAKI. There is no gold standard for early detection of SAKI and limited treatment for patients who have already developed SAKI. Small RNA (microRNA, miRNA) is a non-coding RNA that can regulate its target genes in the process of transcription. Previous studies have explored miRNA as a biomarker and therapeutic target for SAKI. This article will summarize the current knowledge of miRNA as a biomarker and therapeutic targets for SAKI.

  Key words: Sepsis-associated acute kidney injury；micro-RNA；Biomarkers；target spot ；

  Submit time: 8 October 2024

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• 颜林朗, Fan Heng. The application value of proenkephalin 119-159 in septic acute kidney injury. 2024. doi: 10.12201/bmr.202408.00070

  YaQin Hao, YunFeng Hu, Jing Hao, Xin Zhao. Research of circular RNA and autophagy in gastric cancer. 2023. doi: 10.12201/bmr.202304.00001

  He Man, Du Jie, Yang Lei, Li Bin, Yang Yi, Xu Shi, Chai Chen. The cardiovascular effects of irisin in the rostral ventrolateral medulla of septic rats. 2020. doi: 10.12201/bmr.202011.00002

  Li Hang jian, Tong Ming jiong. . 2024. doi: 10.12201/bmr.202409.00056

  Cai Xudong. Macrophage Polarization Affects Chronic Kidney Disease:Based on Theory of “Harmful Hyperactivity and Responding Inhibition”. 2024. doi: 10.12201/bmr.202407.00027

  jiangli. . 2024. doi: 10.12201/bmr.202409.00032

  Zhou lifang, Lv Haiyuan, Shao Jiaxian, Yin Wenqiang, Yu Yuncong, Ma Dongping, Chen Zhongming. A quantitative study of Chinas village clinic doctor policy since the new medical reform: based on policy tools, targets and strength. 2022. doi: 10.12201/bmr.202203.00011

  . 2024. doi: 10.12201/bmr.202410.00044

  Jing ZHAO, Junxia HUANG, Xiuhua TANG, Hong WANG. The role of HOXA11-AS/miR-149-3p pathway in the malignant phenotype of lung squamous cell carcinoma. 2022. doi: 10.12201/bmr.202204.00005

  WangZhiyuan, Mengling, Shijuan, LiuYuanyuan, LiRuidi, LiWenxin, AnShuhong. Expression and the role of TFF3 in lung adenocarcinoma based on bioinformatics analysis. 2024. doi: 10.12201/bmr.202403.00019

• ID	Submit time	Number	Download
  1	2024-08-10	bmr.202410.00011V1	Download

• Public  Anonymous  To author only Submit Comments