Imaging factor analysis of reversible ischemic lesionin cranial CT after mechanical thrombectomy for acute anterior circulation large vessel occlusion

DOI: 10.12201/bmr.202503.00006

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  Abstract: Objective To explore the imaging factor analysis of reversible ischemic edema on cranial CT after mechanical thrombectomy（MT） for acute anterior circulation large vessel occlusion(ALVOS). Methods Patients with ALVOS who underwent MT and were admitted to the Department of Neurology of Jiaxing First Hospital from June 2022 to July 2024 were collected. Cranial CT was used to assess the presence of reversible ischemic edema after the operation. Baseline clinical data of the patients were collected. Multivariate logistic regression model was used to analyze the independent risk factors for reversible ischemic edema on cranial CT after MT for ALVOS; receiver operating characteristic (ROC) curve was constructed to evaluate its predictive value for reversible ischemic edema on cranial CT after MT for ALVOS. Results A total of 142 patients were included in the study, with 120 cases in the irreversible ischemic edema group and 22 cases in the reversible ischemic edema group, with an incidence rate of 15.5%. Binary multivariate logistic regression analysis showed that age (OR = 1.111, 95% CI: 1.017, 1.241, P = 0.031) and time from onset to puncture (OR = 1.050, 95% CI: 1.030, 1.086, P = 0.001) were independent risk factors for reversible ischemic edema on cranial CT after MT for ALVOS. ROC curve analysis showed that age and time from onset to puncture had good predictive value for reversible ischemic edema on cranial CT after MT for ALVOS,area under the curve = 0.989, sensitivity was 93.3%, specificity was 100%. Conclusion The low-density area in the ischemic region on cranial CT after MT for ALVOS may be reversible. Younger age and shorter time from onset to puncture in MT patients may be related to reversible ischemic edema on cranial CT after the operation.

  Key words: Stroke；Mechanical Thrombectomy；Cranial CT；Reversible；Ischemic lesioni

  Submit time: 3 March 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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