• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

Clinical efficacy and safety of Esomeprazole combined with Biling Weitong granules in the treatment of EPS

Corresponding author: Zhou Shuping, hnyyzsp@126.com
DOI: 10.12201/bmr.202501.00052
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: Objective To investigate the clinical efficacy and safety of esomeprazole combined with Biling weitong granules in the treatment of epigastric pain syndrome (EPS), and to provide reference for the comprehensive treatment of EPS. Methods 114 patients with EPS treated in the First Affiliated Hospital of Anhui University of Science and Technology from January 2024 to June 2024 were selected and randomly divided into 57 observation group and 57 control group. The control group was given oral esomeprazole enteric-coated tablet, and the observation group was given combined treatment with Biling Weitong granule on the basis of the control group, and the treatment was continued for 8 weeks. Peripheral blood of patients in the two groups were collected before treatment and 8 weeks after treatment, and the level of gastrin-17 (G-17) in peripheral blood of patients in the two groups was detected respectively. At the same time, the degree of middle-upper abdominal pain and/or burning sensation, weekly frequency and ad

    Key words: : functional dyspepsia; Upper abdominal pain syndrome; Biling weitong granules; Esomeprazole; Clinical efficacy and safety

    Submit time: 18 January 2025

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  • ID Submit time Number Download
    1 2024-10-15

    bmr.202501.00052V1

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Wang Yeliu, Zhou Shuping. Clinical efficacy and safety of Esomeprazole combined with Biling Weitong granules in the treatment of EPS. 2025. biomedRxiv.202501.00052

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