Progress in the study of the effect of intestinal microecological changes on the prognosis of elderly sepsis patients

Corresponding author: Qin Chao, 18338981571@163.com

DOI: 10.12201/bmr.202501.00041

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  Abstract: Sepsis is a systemic inflammatory response syndrome caused by infection, which is often accompanied by high mortality and multiple complications. Recent studies have shown that intestinal microecology plays a crucial role in the induction, progression and regression of sepsis. Due to the gradual decline of the immune system function and the accompanying multiple underlying diseases in the elderly population, the gut microbiota of elderly sepsis patients are more likely to undergo significant changes under the influence of multiple factors, and these changes may affect the course and prognosis of sepsis, therefore, the study of intestinal microecological changes is of great significance in improving the survival of elderly sepsis patients.

  Key words: Elderly patients; Sepsis; Gut microbiota; Dysbiosis of microbiota; Inflammatory response; Immune system; Fecal microbiota transplantation; Improvement in prognosis

  Submit time: 15 January 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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