Research progress of IL-37 in respiratory diseases

Corresponding author: FANG Zhensheng, fzsent@163.com

DOI: 10.12201/bmr.202501.00038

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  Abstract: As a novel anti-inflammatory cytokine in the Interleukin-1 (IL-1) family, Interleukin-37 (IL-37) is highly expressed in multiple systems and diseases, and is clinically inextricably linked to inflammation and tumors. It has been found that IL-37 plays an obvious regulatory role in the pathophysiological process of respiratory diseases. This article summarizes the mechanism of action of IL-37 in common respiratory diseases of the respiratory system, research progress and its therapeutic potential.

  Key words: Interleukin-37; signal transduction pathway; inflammatory response; respiratory diseases

  Submit time: 14 January 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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