The research progress on the association between MMP-9 and schizophrenia and its therapeutic prospects.

DOI: 10.12201/bmr.202407.00065

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  Abstract: Matrix metalloproteinase-9 (MMP-9) is a key zinc-dependent endoprotease that can degrade a variety of extracellular matrix proteins and participate in the regulation of normal physiological proces-ses (such as cell migration, tissue remodeling, etc.) and a variety of pathologi-cal process. Research shows that MMP-9 plays an important regulatory role in the occurrence and development of various diseases and has become a pote-ntial target for disease diagnosis and treatment. These findings have attracted scholars attention to the potential of MMP-9 as an immunological marker for schizophr-enia. This article aims to review the research progress on the relatio-nship between MMP-9 and schizophrenia at home and abroad in recent years, summarize the current r

  Key words: schizophrenia; matrix metalloproteinase-9; risk; inflammation

  Submit time: 28 July 2024

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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