Research progress of neuroinflammatory response and postoperative delirium in patients

Corresponding author: Liu Yong, doctorliuyong@163.com

DOI: 10.12201/bmr.202407.00037

•  

  Abstract: 【】:Postoperative Delirium (POD) is an acute onset of cognitive dysfunction, mainly manifested by memory loss, disorientation and impairment of consciousness, and can even increase the risk of death. POD resulted in a series of adverse consequences such as prolonged hospital stay, increased hospital costs, and increased complications. Neuroinflammatory response is closely related to the occurrence of POD, which induces cerebral cognitive dysfunction by mediating a series of pathological processes such as microglia activation and synaptic remodeling. Therefore, this article reviews the relationship between neuroinflammatory response and POD occurrence, in order to provide reference for the research and prevention of POD.

  Key words: Postoperative Delirium; Neuroinflammatory response; Blood-brain Barrier

  Submit time: 17 July 2024

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• Mo Wei, Xiang Ya, Liao Qiujiao, He Liu, Ling Chaoling, Lu Qixiang, Liu Fangyin. Research progress on risk prediction model of postoperative delirium in elderly patients with hip fractureWEI Yunshi1? MO Wei1? XIANG YA1? LIAO Qiujiao1? HE Liu2? LING Chaoling2? LU Qixiang2? LIU Fangyin3▲. 2024. doi: 10.12201/bmr.202409.00029

  Bao Kaiwen. Research progress on DNA damage and immune response in autoimmune diseases. 2024. doi: 10.12201/bmr.202410.00007

  shenzhouji, guofei. Research progress of histone modification and DNA methylation in diabetes nephropathy. 2024. doi: 10.12201/bmr.202407.00011

  zhaochengyu. Research Progress on the Relationship between Hyperuricemia and Diabetic Peripheral Neuropathy. 2024. doi: 10.12201/bmr.202408.00019

  TANG Yanghua. Observation on the effect of muscle energy technique in postoperative rehabilitation of ankle fracture. 2024. doi: 10.12201/bmr.202409.00014

  XU Jianhong. Study of dexmedetomidine on intestinal barrier protection in hypertensive patients. 2024. doi: 10.12201/bmr.202408.00045

  The predictive value ofperipheral blood inflammatory makers for lower extremity deep venous thrombosis after hip fracture surgery in patients. 2024. doi: 10.12201/bmr.202408.00016

  Wangyubing. . 2024. doi: 10.12201/bmr.202408.00071

  lijieping. Research Advances in the Mechanism of Mitochondrial Damage in Heatstroke. 2024. doi: 10.12201/bmr.202410.00030

  LUAN Zhi-Yong. Research progress of stem cell therapy for Hirschsprung disease. 2024. doi: 10.12201/bmr.202410.00021

• ID	Submit time	Number	Download
  1	2024-07-04	bmr.202407.00037V1	Download

• Public  Anonymous  To author only Submit Comments