通讯作者: 李志瑜, sophyyy0653@sina.com.cn

DOI：10.12201/bmr.202504.00025

Analysis Of Infection Status And Drug Sensitivity Of Mycoplasma And Chlamydia In 2324 Outpatients

• 摘要：目的 分析2324例门诊患者解脲脲原体（ureaplasma urealyticum, UU）、人型支原体（mycoplasma hominis, MH）和沙眼衣原体（chlamydia trachomatis, CT）的感染情况及耐药性，为泌尿生殖道非淋菌性感染的防治工作提供参考。方法 采用液体培养法检测UU和MH并进行药敏实验，采用乳胶法检测CT，并对结果进行统计分析。结果 2324例送检患者总阳性率为43.3%，女性阳性率显著高于男性，UU、MH和CT阳性检出率分别为44.8%、10.0%和1.8%。单一感染患者中，UU阳性检出率最高（31.8%）。混合感染患者中，UU+MH阳性检出率（8.2%）最高。UU、MH和CT阳性检出率最高的年龄组分别是41~50岁、≤20岁和21~30岁。981例阳性患者药敏实验结果显示，UU和MH对强力霉素、米诺环素和交沙霉素敏感性高，敏感率依次为97.2%、96.9%和95.4%。结论 我院门诊泌尿生殖道非淋菌性感染人群主要是中青年（21~40岁），检出的病原体以UU为主，女性检出率高于男性，根据支原体药敏结果，建议选用强力霉素、米诺环素和交沙霉素治疗。

  关键词： 解脲脲原体; 人型支原体; 沙眼衣原体; 性传播疾病

   

  Abstract: Objective To analyze the infection and drug resistance of Ureaplasma urealyticum (UU), Mycoplasma hominis (MH) and Chlamydia Trachomatis (CT) in 2324 outpatients, and to provide reference for the prevention and treatment of nongonococcal infections in urogenital tract. Methods UU and MH were detected by liquid culture method and drug sensitivity tests were carried out, and CT was detected by latex method, and the results were statistically analyzed. Results The total positive rate of 2324 patients submitted for examination was 43.3%, and the positive rate in women was significantly higher than that in men. The positive detection rates of UU, MH and CT were 44.8%, 10.0% and 1.8% respectively. Among patients with single infection, the UU positive detection rate was the highest (31.8%). Among patients with mixed infections, the positive detection rate of UU+MH (8.2%) was the highest. The age groups with the highest positive rates of UU, MH and CT were 41 - 50 years old, ≤20 years old and 21 - 30 years old respectively. Drug sensitivity test results of 981 positive patients showed that UU and MH were highly sensitive to doxycycline, minocycline and josamycin, with the sensitivity rates of 97.2%, 96.9% and 95.4% respectively. Conclusion The patients with nongonococcal infection in urogenital tract in our hospital are mainly young and middle-aged (21-40 years old). UU is the main pathogen detected, and the detection rate of female is higher than that of male. According to the drug sensitivity results of mycoplasma, it is suggested to choose doxycycline, minocycline and josamycin for treatment.

  Key words: ureaplasma urealyticum; mycoplasma hominis; chlamydia trachomatis; sexually transmitted diseases

  提交时间：2025-04-09

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• 序号	提交日期	编号	操作
  1	2025-02-23	bmr.202504.00025V1	下载

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