付学锋, 曾磊, 江渊, 王美燕, 将冰晶, 章艳斐. 皮肤镜联合快速冰冻切片检查在头面部皮肤肿瘤治疗中的应用. 2025. biomedRxiv.202502.00028
皮肤镜联合快速冰冻切片检查在头面部皮肤肿瘤治疗中的应用
通讯作者: 付学锋, Xuefengfu123@163.com
DOI:10.12201/bmr.202502.00028
Clinical application of dermatoscope combined with rapid frozen section examination in the treatment of head and face skin tumors.
-
摘要:目的 评估皮肤镜联合快速冰冻切片检查的方法在头面部皮肤肿瘤治疗中的应用价值。方法 回顾分析2019年6月至2023年12月金华市中心医院皮肤科收治的123例头面部皮肤肿瘤患者,分别采用术前皮肤镜联合术中快速冰冻切片检查方法和皮肤活检术联合术中快速冰冻两种方式进行手术治疗。统计分析比较两种方法的手术治愈率及皮肤镜图像诊断、快速冰冻切片诊断与石蜡切片的诊断符合率。结果 术前皮肤镜联合术中快速冰冻切片检查方法和术前皮肤活检联合术中快速冰冻的两种方法在头面部皮肤肿瘤治疗中效果无明显疗效差异。皮肤镜图像分析技术与石蜡切片的诊断符合率为91.36%,快速冰冻切片检查诊断符合率为98.37%。所有病例术中快速冰冻切片及术后石蜡切片均报告基底及切缘阴性,术后随访6月以上未见复发情况。结论 在头面部皮肤肿瘤的手术治疗中,皮肤镜联合术中快速冰冻切片检查的方法效果明显,可替代术前皮肤活检,值得临床推广。
Abstract: Objective To evaluate the application value of dermatoscope combined with quick frozen section examination in the treatment of head and face skin tumors. Methods Retrospective analysis of 123 patients with head and neck skin tumors admitted to the Dermatology Department of Jinhua Municipal Central Hospital from June 2019 to December 2023. They were treated using a combination of skin biopsy and intraoperative rapid frozen section as well as preoperative dermoscopy and intraoperative rapid frozen section assessment.The surgical cure rate of the two methods and the coincidence rate of dermatoscope image diagnosis, quick frozen section diagnosis and paraffin section diagnosis were statistically analyzed and compared.Results There is no significant difference between preoperative dermoscopy combined with intraoperative quick frozen section examination and preoperative skin biopsy combined with intraoperative quick frozen section examination in the treatment of head and face skin tumors. The coincidence rate of dermoscopy image analysis technology and paraffin section diagnosis is 91.36%, and the coincidence rate of quick-frozen section examination diagnosis is 98.37%. All cases reported negative in basal margins by intraoperative quick frozen section and postoperative paraffin section, and no recurrence was found after 6 months follow-up. Conclusion In the surgical treatment of head and face skin tumors, dermoscopy combined with intraoperative rapid frozen section examination has obvious effect, which can replace preoperative skin biopsy and is worthy of clinical promotion.
Key words: dermatoscope; image analysis; technology,quick; frozen section,pathological; diagnosis,skin; tumor提交时间:2025-02-17
版权声明:作者本人独立拥有该论文的版权,预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。 -
图表
-
王楠, 王国蓉, 施雯停, 李清炉. 维持性血液透析患者皮肤瘙痒影响因素的系统评价和Meta分析. 2024. doi: 10.12201/bmr.202410.00043
徐子茜, 林秉奖, 邱勰, 黄华, 许素玲, 陆凌怡. 多组学分析MZT2A在皮肤黑色素瘤中的作用. 2024. doi: 10.12201/bmr.202412.00012
秦金华, 刘超毅, 洪源, 曾嘉慧. AIGC全病程消息推送平台在肿瘤手术室的应用. 2024. doi: 10.12201/bmr.202412.00036
.河北大学附属医院消化内科 河北 保定, 杰. 基于深度学习的人工智能技术在胃肠间质瘤中的应用进展. 2024. doi: 10.12201/bmr.202411.00057
王也煜, 常玮, 李军. 内镜检查对声带白斑病理诊断的预测价值研究. 2024. doi: 10.12201/bmr.202408.00023
高亮, 吴洁, 周桢干, 夏鸣, 孙宏杰, 周凯, 张庭荣, 李绍山. 垂体神经内分泌肿瘤手术治疗的研究进展. 2025. doi: 10.12201/bmr.202501.00074
饶效, 薛剑波, 周志有. Mimics三维重建技术联合Hookwire定位在肺小结节胸腔镜手术中的应用价值. 2025. doi: 10.12201/bmr.202503.00051
翁文辉, 方瑞, 张开茂. 鱼骨图分析法应用于抗肿瘤药物配置效果. 2024. doi: 10.12201/bmr.202408.00025
蔡嘉辉, 农光任, 李鸿海, 卢保德, 黄勇平. 双镜联合治疗肾或输尿管上段结石的疗效分析. 2024. doi: 10.12201/bmr.202408.00067
雷亚典, 王海燕. 肿瘤免疫微环境影响T细胞的功能:聚焦ICB的局限性和联合治疗方案. 2024. doi: 10.12201/bmr.202412.00083
-
序号 提交日期 编号 操作 1 2025-01-11 bmr.202502.00028V1
下载 -
-
公开评论 匿名评论 仅发给作者
引用格式
访问统计
- 阅读量:85
- 下载量: 0
- 评论数:0