通讯作者: 李绍山, 45316016@qq.com

DOI：10.12201/bmr.202501.00074

Advancements in Surgical Treatment Research for Pituitary Neuroendocrine Tumors

• 摘要：随着社会对健康需求的日益增长以及MRI等影像学技术的飞速发展，垂体神经内分泌肿瘤在人群中的检出率显著提升，已成为发病率居第二位的颅内肿瘤类型，约占15%，其人口发病率为8.2%至14.7%。手术切除目前是治疗除泌乳素型外其他类型垂体神经内分泌肿瘤的首选方法。手术治疗的目的主要包括：切除瘤体缓解长期压迫周围结构产生的临床症状；保留正常垂体功能；纠正内分泌功能紊乱；明确肿瘤病理组织学。目前临床实践中主流术式包括：经颅手术和经鼻蝶手术。本文旨在讨论垂体、垂体肿瘤膜性结构解剖、垂体神经内分泌肿瘤手术方式的研究进展，将垂体、垂体肿瘤解剖和手术实践更好的结合起来，以提高神经外科术者对现有垂体神经内分泌肿瘤手术方法的理解，为患者带来更多的益处。

  关键词： 垂体神经内分泌肿瘤；垂体膜性结构；假包膜；神经内镜 ；手术入路

   

  Abstract: With the increasing societal demand for health and the rapid advancements in imaging technologies, such as MRI, the detection rate of pituitary neuroendocrine tumors in the population has significantly increased. These tumors have now become the second most common type of intracranial neoplasm, representing approximately 15% of all cases, with an incidence rate ranging from 8.2% to 14.7% within the general population. Surgical resection remains the preferred treatment modality for pituitary neuroendocrine tumors, excluding prolactinomas. The primary goals of surgical intervention include the removal of the tumor mass to alleviate clinical symptoms arising from prolonged compression of adjacent structures, preservation of normal pituitary function, correction of endocrine dysfunction, and precise histopathological characterization of the tumor.This article aims to discuss the advancements in the research of pituitary and pituitary tumor membranous anatomy as well as surgical approaches for pituitary adenomas. It seeks to better integrate the anatomical understanding of the pituitary and pituitary tumors with surgical practice to enhance neurosurgeons comprehension of existing surgical methods for pituitary adenomas, thereby providing greater benefits to patients.Keywords: Pituitary Neuroendocrine Tumors；Sellar Membranous Structures；Pseudocapsule；Neuroendoscopy；Surgical Approach

  Key words: Keywords: Pituitary Neuroendocrine Tumors；Sellar Membranous Structures；Pseudocapsule；Neuroendoscopy；Surgical Approach

  提交时间：2025-01-23

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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• 序号	提交日期	编号	操作
  2	2025-01-02	bmr.202501.00074V2	下载
  1	2025-01-02	bmr.202501.00074V1	下载

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