• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

Professor Liu Likun experience in Treating Opioid relatedConstipation in Cancer Patients Based on the Three Jiao Differentiation

Corresponding author: Liu Likun, llkun133@126.com
DOI: 10.12201/bmr.202504.00042
Statement: This article is a preprint and has not been peer-reviewed. It reports new research that has yet to be evaluated and so should not be used to guide clinical practice.
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    Abstract: Patients with advanced cancer pain often experience constipation due to the use of opioid drugs, which seriously affects the quality of life and treatment compliance of cancer patients. Western medicine treatment for OIC mainly focuses on symptomatic treatment, which can easily lead to drug addiction and reduce long-term efficacy. Traditional Chinese Medicine believes that opioid drugs have a sour and astringent taste, with a strong sense of astringency that can easily block the circulation of qi and blood, which is a manifestation of drug toxicity. Professor Liu Likun believes that the pathogenesis of opioid related constipation in cancer patients is due to “sanjiao” block and loss of normal fluid distribution. Professor Liu has shown good therapeutic effects in treating cancer opioid related constipation from the perspective of triple focus in clinical practice.

    Key words: sanjiao; Opioid related constipation; Drug toxicity; Famous Doctor Experience

    Submit time: 15 April 2025

    Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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    1 2025-03-10

    bmr.202504.00042V1

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Liu Jinjing, Zhou Bowen, Yanmeijun, Li XiaoLi, Hao Shulan, Liu Likun. Professor Liu Likun experience in Treating Opioid relatedConstipation in Cancer Patients Based on the Three Jiao Differentiation. 2025. biomedRxiv.202504.00042

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