Construction and preliminary application of liver cirrhosis special disease database

Corresponding author: WU Xiao-ying, wuxy227@mail.sysu.edu.cn

DOI: 10.12201/bmr.202104.00014

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  Abstract: High-quality special disease database is an important basic support for the analysis and utilization of special disease of big data. The construction of special disease databases in China have just started. For the sake of the construction of liver cirrhosis special disease database at the Third Affiliated Hospital of Sun Yat-sen University, we analyzed the gastroenterologists’ demand of clinical research and application for the liver cirrhosis special disease database; then with the support of the gastroenterology department and clinical data center, combining with the medical business systems and the follow-up system, we established the liver cirrhosis special database. This database covers more than 20,000 cases of liver cirrhosis patients, including routine electronic medical records, pathological data, image data, biological samples data and so on, they involve physiological, biochemical, treatment, examination, nursing and other multi-dimensional information, with a total of 729 indicators. Based on this database, we are carrying out a series of clinical application projects, such as retrospective or prospective cohort, and prognosis studies based on multimodal data for liver cirrhosis patients. The construction of this liver cirrhosis special database provides experience and reference for the construction and application of domestic clinical special database, provides strong data support for the scientific research, clinical decision-making and improvement of medical service quality of liver cirrhosis, and is of great significance to assist to improve the standard and level of clinical diagnosis and treatment of liver diseases.

  Key words: Special Disease Database; Liver Cirrhosis; Disease Database; Big Data of Special Disease

  Submit time: 25 May 2021

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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