杨雅玲, 梁瑞文. 基于“标本虚实”理论浅谈克罗恩病肛瘘的论治经验. 2025. biomedRxiv.202503.00003
基于“标本虚实”理论浅谈克罗恩病肛瘘的论治经验
通讯作者: 梁瑞文, 2860435439@qq.com
DOI:10.12201/bmr.202503.00003
A Brief Discussion on the Treatment Experience of Anal Fistula in Crohns Disease Based on the Theory of Root and Manifestation, Deficiency and Excess
Corresponding author: liangruiwen, 2860435439@qq.com
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摘要:克罗恩病是一种目前病因尚未完全明确的慢性非特异性肠道炎症性疾病,其发病机制较复杂,且在临床上的表现也呈现出多样化的特点。部分患者在疾病初期,主要以肛周局部的症状作为首发表现,尤其是肛周瘘管最为常见。在中医的理论体系中,克罗恩病所引起的肛瘘被归类为“本虚标实”的范畴,具体而言,是以脾肾两虚作为其内在的根本原因,而湿毒之邪下注至肛门区域则表现为外在的标证。由于克罗恩病的病情变化多端,因此在治疗策略上,特别强调整体与局部治疗相结合,通过全面评估患者的疾病状态,制定出个性化的治疗方案。基于这样的治疗思路,本文对克罗恩病肛瘘在临床治疗中的宝贵经验进行了系统而简要的总结,旨在为临床医生提供有益的参考和借鉴。
Abstract: Crohns disease is a chronic and non-specific intestinal inflammatory disorder. Up to now, its exact etiology remains incompletely understood, and the pathogenesis is rather intricate. Clinically, it exhibits a wide spectrum of diverse manifestations. For some patients, at the early stage of the disease, the initial symptoms often mainly present as local perianal symptoms, among which perianal fistulas are particularly prevalent.In the theoretical framework of traditional Chinese medicine, the anal fistulas induced by Crohns disease are categorized into the realm of root deficiency and manifestation excess. To be more specific, the deficiency of both the spleen and the kidney serves as the fundamental internal cause. The spleen, being responsible for the transportation and transformation of nutrients, and the kidney, which is crucial for the bodys vital essence and energy, when deficient, weaken the bodys overall constitution. On the other hand, the downward deposition of dampness-toxicity evil qi in the perianal area is the external manifestation. Dampness and toxicity can obstruct the normal flow of qi and blood, leading to local inflammation and the formation of fistulas.Given the highly variable nature of Crohns disease, the treatment strategy emphasizes the integration of holistic and local therapies. A comprehensive assessment of the patients disease state, including the severity of the intestinal inflammation, the condition of the perianal fistula, and the patients overall physical constitution, is essential for formulating a personalized treatment plan. This may involve a combination of traditional Chinese medicine treatments such as herbal medicine to tonify the spleen and kidney and clear away dampness and toxicity, as well as surgical interventions for the management of the anal fistula.In conclusion, understanding the concept of root and manifestation, deficiency and excess is of great significance in the treatment of anal fistulas in Crohns disease. It provides a unique perspective for guiding clinical practice and developing more effective treatment approaches to improve the prognosis and quality of life of patients.
Key words: Root and Manifestation, Deficiency and Excess; Anal Fistula in Crohns Disease; Treatmen提交时间:2025-03-03
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序号 提交日期 编号 操作 1 2025-02-07 bmr.202503.00003V1
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