通讯作者: 强群, zaozhu82@126.com

DOI：10.12201/bmr.202412.00072

Meta-analysis of the diagnostic value of ultrasound and MRI in knee osteoarthritis

• 摘要：目的 通过Meta分析评价超声和磁共振成像(MRI)诊断膝骨关节炎(knee osteoarthritis,KOA)的价值。方法 全面检索了PubMed、Cochrane library、Web of Science、CBM、Embase、中国知网、维普数据库和万方医学网等数据库,收集了截止至2024年4月关于超声与MRI诊断KOA的所有研究。两位评审员独立按照预设标准筛选文献、提取数据并评估研究质量。利用Meta-Disc 1.4软件对这些研究进行Meta分析,旨在全面评估超声和MRI在KOA诊断中的有效性。结果 在综合分析中,共纳入14篇文献,涉及1613例患者。纳入研究均以关节镜或手术病理结果作为诊断的金标准。超声在诊断KOA方面的合并敏感度、特异度和诊断比值比分别为0.79、0.82和20.30,而受试者工作特征曲线下面积AUC值为0.89。相比之下,MRI诊断KOA的合并敏感度、特异度和诊断比值比分别为0.88、0.85和42.35,其AUC值为0.92。结论 超声和MRI在KOA的诊断中均展现出较高的准确性,其中MRI的表现略胜一筹。

  关键词： 膝骨关节炎、超声、MRI、Meta分析

   

  Abstract: Objective To evaluate the value of ultrasound and magnetic resonance imaging (MRI) in the diagnosis of knee osteoarthritis (KOA) by Meta-analysis. Methods A comprehensive literature search was conducted across various databases, including PubMed, the Cochrane Library, Web of Science, CBM, Embase, CNKI (China National Knowledge Infrastructure), VIP (China Science and Technology Journal Database), and WanFang Database of Medicine, to gather all relevant studies on the use of ultrasound and MRI in KOA up to April 2024. Two independent reviewers meticulously screened the literature according to predefined criteria, extracted data, and assessed the quality of the studies. The Meta-Disc 1.4 software was employed to conduct a meta-analysis of these studies, with the objective of providing a comprehensive evaluation of the effectiveness of ultrasound and MRI in the diagnosis of KOA. Results In the comprehensive analysis, a total of 14 studies involving 1613 patients were included. All included studies used arthroscopy or surgical pathology as the gold standard for diagnosis. The pooled sensitivity, specificity, and diagnostic odds ratio (DOR) for ultrasound in diagnosing KOA were 0.79, 0.82, and 20.30, respectively, with an AUC curve of 0.89 for the area under the subjects work characterization curve. In comparison, the pooled sensitivity, specificity, and DOR for MRI in diagnosing KOA were 0.88, 0.85, and 42.35, respectively, with an AUC of 0.92 under the SROC curve. Conclusion Ultrasound and MRI have good accuracy in the diagnosis of KOA, but MRI is superior to ultrasound.

  Key words:

  提交时间：2024-12-29

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• 序号	提交日期	编号	操作
  1	2024-11-07	bmr.202412.00072V1	下载

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