• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

清肝宁心制动方治疗儿童注意缺陷多动障碍心肝火旺型的临床观察

通讯作者: 杨青, 17855364086@163.com
DOI:10.12201/bmr.202412.00051
声明:预印本系统所发表的论文仅用于最新科研成果的交流与共享,未经同行评议,因此不建议直接应用于指导临床实践。

Clinical Observation of Qinggan Ningxin Zhidong Prescription in the Treatment of Attention Deficit Hyperactivity Disorder with Heart-Liver Fire Blazing Syndrome

Corresponding author: YANG Qing, 17855364086@163.com
  • 摘要:目的:观察清肝宁心制动方对多动症儿童(心肝火旺型)临床症状的改善作用。方法:选取2023年3月~2024年3月在芜湖市中医医院就诊的50例多动症患儿,依据随机数字表法分为对照组和试验组各25例。对照组予以静灵口服液治疗,试验组予以清肝宁心制动方治疗,治疗2个月。观察对比两组疗效及治疗前后SNAP-Ⅳ评分、中医证候积分及血清皮质醇(COR)水平。结果:试验组的总有效率高于对照组(P<0.05);两组患儿SNAP-Ⅳ评分、中医证候积分均降低,两组患儿血清COR水平升高,其中试验组疗效更显著(P<0.05)。结论:清肝宁心制动方可以有效改善患儿的临床症状,调节血清COR水平,提高临床疗效。

    关键词: 清肝宁心制动方;儿童;注意缺陷多动障碍;心肝火旺证;临床疗效

     

    Abstract: Objective: To observe the improvement effect of Qinggan Ningxin Zhi Dong Fang on the clinical symptoms of children with attention deficit hyperactivity disorder (ADHD, heart-liver fire type). Methods: Fifty children with ADHD diagnosed and treated at Wuhu City Traditional Chinese Medicine Hospital from March 2023 to March 2024 were selected and divided into a control group and an experimental group of 25 cases each using the random number table method. The control group was treated with Jingling Oral Liquid, while the experimental group was treated with Qinggan Ningxin Zhi Dong Fang for a period of 2 months. The efficacy of the two groups and the SNAP-IV scores, traditional Chinese medicine symptom scores, and serum cortisol (COR) levels before and after treatment were observed and compared. Results: The total effective rate of the experimental group was higher than that of the control group (P<0.05); the SNAP-IV scores and traditional Chinese medicine symptom scores of children in both groups were reduced, and the serum COR levels of children in both groups were increased, with the experimental group showing more significant effects (P<0.05). Conclusion: Qinggan Ningxin Zhi Dong Fang can effectively improve the clinical symptoms of children, regulate serum COR levels, and enhance clinical efficacy.

    Key words: Qinggan Ningxin Zhidong prescription; children; attention deficit hyperactivity disorder; heart-liver fire blazing syndrome; clinical efficacy

    提交时间:2024-12-23

    版权声明:作者本人独立拥有该论文的版权,预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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    1 2024-09-29

    bmr.202412.00051V1

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伍静, 杨青. 清肝宁心制动方治疗儿童注意缺陷多动障碍心肝火旺型的临床观察. 2024. biomedRxiv.202412.00051

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