通讯作者: 徐克菲, 825913966@qq.com

DOI：10.12201/bmr.202409.00041

A case of treating lupus nephritis in a child with Belizumab combined with traditional Chinese medicine syndrome differentiation formula

• 摘要：目的：分析1例狼疮性肾炎患儿的诊治经过，探讨生物制剂联合中药辨证方治疗狼疮性肾炎的临床疗效及安全性。方法：报道1例以“肉眼血尿”就诊的狼疮性肾炎患儿的临床表现、实验室检查以及诊治经过，通过对治疗前后临床证候的改善、基础用药的调整以及血清补体、尿检等指标进行总结分析，讨论贝利尤单抗联合中药辨证方在治疗儿童狼疮性肾炎的临床疗效、安全性以及优势所在。结果：贝利尤单抗联合中药辨证方治疗，可快速控制狼疮性患儿的临床证候，血尿、蛋白尿水平以及疾病活动度，减少疾病复发。结论：对于难治性狼疮性肾炎，可采用贝利尤单抗联合中药辨证方治疗，以控制病情，减少疾病复发。

  关键词： 狼疮性肾炎; 肉眼血尿; 中西医结合

   

  Abstract: Objective: To analyze the diagnosis and treatment process of a child with lupus nephritis, and explore the clinical efficacy and safety of biological preparations combined with traditional Chinese medicine syndrome differentiation formulas in the treatment of lupus nephritis. Method: Report on the clinical manifestations, laboratory tests, and diagnosis and treatment process of a child with lupus nephritis who presented with gross hematuria. Through summarizing and analyzing the improvement of clinical symptoms before and after treatment, adjustment of basic medication, serum complement, urine tests, and other indicators, discuss the clinical efficacy, safety, and advantages of belimumab combined with traditional Chinese medicine syndrome differentiation formula in the treatment of pediatric lupus nephritis.Result: The combination of belimumab and traditional Chinese medicine syndrome differentiation formula can quickly control the clinical symptoms, hematuria, proteinuria levels, and disease activity of children with lupus, and reduce disease recurrence. Conclusion: For refractory lupus nephritis, the combination of belimumab and traditional Chinese medicine syndrome differentiation formula can be used to control the condition and reduce disease recurrence.

  Key words: Lupus nephritis; Visual hematuria; Integrated Traditional Chinese and Western Medicine

  提交时间：2024-09-21

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• 序号	提交日期	编号	操作
  1	2024-05-23	bmr.202409.00041V1	下载

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