通讯作者: 陶肖樱, 434599718@qq.com

DOI：10.12201/bmr.202410.00076

YANG Daoling, ZHOU Yibo, WANG Xidan, CHEN Jingwan, CHEN Fuhua, TAO XiaoyingFirst-author’s address: Department of Ultrasound Medicine, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, 321000, China

• 摘要：目的 探讨胎儿心脏定量分析技术(fetal HQ)评估妊娠期高血压患者胎儿心脏形态和功能的临床应用价值。 方法 选取2020年3月至2024年3月孕龄20-40周娠期高血压疾病孕妇85例作为观察组,根据孕妇的血压、尿蛋白及症状将观察组分为妊娠期高血压组(GH)35例,子痫前期轻度组(MPE)28例、子痫前期重度组(SPE)22例；另随机选择孕龄匹配的正常孕妇150例作为对照组(NOR)；应用fetal HQ技术获取两组胎儿心脏形态指标和功能指标并进行统计分析。 结果 260例胎儿动态四腔心图像中,成功采集235例数据,成功率90%。同一患者胎儿心脏左右室FAC、Tei指数、GLS比较,左、右室GLS、FAC差异有统计学意义(P＜0.05),右室GLS、FAC大于左室。各组患者形态指标GSI差异有统计学意义(P＜0.05),SPE组患者胎儿心脏更圆。各组患者左右室FAC、Tei指数、GLS比较,右室GLS、右室Tei指数差异有统计学意义(P＜0.05),S-PE组、M-PE组患者右室GLS绝对值低于NOR组,S-PE组患者右室Tei指数大于NOR组患者。 结论 Fetal HQ技术可快速、方便地定量评估胎儿心脏形态和功能。妊娠期高血压不仅使胎儿心脏形态发生变化,而且影响胎儿心脏功能,且对胎儿右心系统的影响大于左心。

  关键词： 妊娠期高血压；胎儿心脏定量分析技术；纵向应变；面积变化率；整体球形指数; ; ; ; 

   

  Abstract: Objective To explore the clinical application value of fetal quantitative analysis technology (fetal HQ) in evaluating the morphology and function of fetal heart in hypertensive disorders of pregnancy. Method A total of 85 women with gestational hypertension during the gestational age of 20-40 weeks from March 2020 to March 2024 had been selected as the experimental group. According to the blood pressure, urine protein, and symptoms of the pregnant women, the experimental group was divided into 35 cases of gestational hypertension group (GH), 28 cases of mild preeclampsia group (MPE), and 22 cases of severe preeclampsia group (SPE). Additionally, 150 normal pregnant women with matched gestational age were randomly selected as the control group (NOR). The fetal HQ technique was adopted to obtain cardiac morphological and functional indicators of both groups, and statistical analysis was conducted. Result Among 260 cases of fetal dynamic four-chamber heart images, data from 235 cases were successfully collected, with a success rate of 90%. Through comparison of the left and right ventricular FAC, Tei index, and GLS of the same patient’s fetal heart, there was a statistically significant difference (P＜0.05) in GLS and FAC between the left and right ventricles, with the right ventricle having a higher GLS and FAC than the left ventricle. In addition, there was a statistically significant difference in GSI in each group (P＜0.05). Patients in the SPE group had rounder fetal hearts. Besides, variance analysis was performed on left and right ventricular FAC, Tei index, and GLS for each group of patients. There was a statistically significant difference in right ventricular GLS and right ventricular Tei index (P＜0.05). The absolute value of right ventricular GLS in the S-PE group and M-PE group was lower than that in the NOR group, while the right ventricular Tei index in the S-PE group was higher than that in the NOR group. Conclusions Fetal HQ technique provides quick and easy quantitative assessment of fetal heart shape and function. Gestational hypertension not only changes the fetal heart morphology, but also affects the fetal heart function, and the fetal right heart system is more affected than than the fetal left heart.

  Key words: Gestational hypertension; fetal heart quantification; longitudinal strain; fractional area change; global spherical index

  提交时间：2024-10-31

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
• html

• 图表

• 田凤, 陈媛, 陈诗琪, 张榕祥, 朱晨阳. ERAS在心脏瓣膜病患者围手术期应用效果的Meta分析. 2024. doi: 10.12201/bmr.202410.00008

  张小娟. 社区医院高血压和糖尿病防治现状研究. 2023. doi: 10.12201/bmr.202311.00002

  王昕. 杨志宏治疗肝阳上亢型高血压性眩晕的临床经验. 2020. doi: 10.12201/bmr.202004.00008

  曹丽敏, 张丽敏, 于欣, 王白石, 刘景利. 血清学指标与阴道彩超鉴别诊断早期异位妊娠、先兆流产的价值. 2024. doi: 10.12201/bmr.202408.00036

  胡铁骊. 互联网中医医院建设现状与发展趋势研究. 2022. doi: 10.12201/bmr.202207.00007

  庞震, 顾继昱, 吴宇飞, 颜仕星, 李汪洋, 孙越. 一种基于三元组抽取策略解决中医诊治高血压医疗实体提取问题的研究. 2021. doi: 10.12201/bmr.202107.00015

  方晢伊, 祝雯珺, 黄葭燕. 全球抗生素耐药性研究进展的文献计量分析. 2022. doi: 10.12201/bmr.202207.00021

  薛琴丹. 健康素养在慢性心力衰竭患者症状负担与疾病不确定感间的调节效应分析. 2024. doi: 10.12201/bmr.202407.00062

  郝梦娟. 虚拟现实技术在自然分娩中的应用现状和展望. 2024. doi: 10.12201/bmr.202408.00048

  李凤姣, 徐建红. 右美托咪定对高血压患者肠屏障保护的研究. 2024. doi: 10.12201/bmr.202408.00045

• 序号	提交日期	编号	操作
  1	2024-09-16	bmr.202410.00076V1	下载

• 公开评论  匿名评论  仅发给作者 提交评论