通讯作者: 叶益平, 352538912@qq.com

DOI：10.12201/bmr.202407.00030

Study on the regularity of medication of Director Ye Yiping in the treatment of lung cancer based on data mining methods

• 摘要：目的 基于中医传承辅助平台(V2.5),深层次挖掘叶益平治疗肺癌的用药规律。方法 收集2022年1月1日至2023年9月30日在丽水市中医院叶益平门诊治疗肺癌患者完整医案200例,录入中医传承辅助平台(V2.5),采用软件的关联规则分析、聚类分析等方法分析叶益平治疗肺癌的用药规律。结果 搜集得到医案200例,记录200首处方,涉及146味中药；所用药物的药性以寒、温、平为主,药味以甘、苦、辛为主,主要归肺、脾、胃、心经；使用频次居前28味的中药依次为羊乳、甘草、丹参、姜半夏、猫人参、浙贝母、茯苓、焦六神曲、石见穿等,得到核心药物组合27组,新方5个。结论 以中医传承辅助系统为平台,应用数据挖掘方法可更深入地挖掘了叶益平治疗肺癌用药规律,临证辨治紧扣肺癌“阴虚瘀毒”核心病机,同时顾护后天脾胃、心身同调,体现了扶正抗癌及中医整体观的中医肿瘤学术思想。

  关键词： 数据挖掘；中医传承辅助平台；肺癌；用药规律；叶益平; 

   

  Abstract: Objective To explore the medication rule of Ye Yiping in the treatment of lung cancer based on TCM inheritance assistance platform (V2.5).Methods From January 1, 2022 to September 30, 2023, 200 complete medical records of patients with lung cancer treated in Ye Yipings outpatient department of Lishui Hospital of Traditional Chinese Medicine were collected and input into the Traditional Chinese Medicine inheritance assistance platform (V2.5). Association rule analysis, cluster analysis and other methods of software were used to analyze Ye Yipings drug use in the treatment of lung cancer.Results 200 medical records were collected and 200 prescriptions were recorded, involving 146 TCM. The medicinal properties of the drugs used are mainly cold, warm and flat, and the taste is mainly sweet, bitter and xin, which mainly belong to lung, spleen, stomach and heart channel. The top 28 Chinese herbs used frequently were goat milk, licorice, salvia miltiorrhiza, ginger pinellia, cat ginseng, Zhejiang Fritillaria, Poria cocos, Jiao Liushenqu, Shi Jianhuan, etc. 27 groups of core drug combinations and 5 new prescriptions were obtained.Conclusion With the TCM inheritance assistance system as the platform, the application of data mining method can further explore the drug use law of Ye Yiping in the treatment of lung cancer. The clinical diagnosis and treatment are closely related to the core pathogenesis of Yin deficiency and stasis toxicity of lung cancer, and at the same time, the acquired spleen and stomach, mind-body harmony are taken care of, which reflects the academic thought of TCM tumor of supporting the right anti-cancer and the holistic view of TCM.

  Key words: data mining；TCM Inheritance Support Platform System；lung cancer; regularity of medication；Ye Yiping

  提交时间：2024-07-15

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• 序号	提交日期	编号	操作
  1	2024-05-23	bmr.202407.00030V1	下载

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