Progress of community-acquired respiratory distress syndrome toxins in Mycoplasma pneumoniae infection in children

Corresponding author: ZHANG Xiao-Hua, zhangxiaohua@ntfybj.com

DOI: 10.12201/bmr.202506.00057

•  

  Abstract: Community-acquired respiratory distress syndrome toxin (CARDS TX) is a relatively stable exotoxin produced by Mycoplasma pneumoniae (MP). Extensive studies in recent years have gradually clarified the structure, distribution, and pathogenic mechanism of this toxin in MP infections, as well as its role in inducing airway hyperresponsiveness and sensitization, and it also provides a reference for the development of MP vaccines against CARDS TX. This article reviews recent research advances in CARDS TX in MP in pediatric Mycoplasma pneumoniae infections, providing new ideas for further understanding the etiology and treatment of MP.

  Key words: Mycoplasma Pneumoniae; Infections; Community-Acquired Respiratory Distress Syndrome Toxin; Airway Hyperresponsiveness; Allergy

  Submit time: 23 June 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• changyanmei, yulijuan, 孟淑萍. The value of Mycoplasma pneumoniae RNA detection in the diagnosis and treatment of Mycoplasma pneumoniae pneumonia in children. 2025. doi: 10.12201/bmr.202506.00025

  Lu jianliang, Feng yuan, Lu yanling. Analysis of clinical characteristics of severe mycoplasma pneumoniae pneumonia in children. 2025. doi: 10.12201/bmr.202505.00038

  马亚鑫, ZHU Xiaowei, Li Shuqiong, Li Yunxiang, Sun Yonghong. MA Yaxin1, LI Shuqiong1, LI Yunxiang1, SUN Yonghong2▲. 2025. doi: 10.12201/bmr.202504.00073

  GENG Gang, LI Shaojun. Mycoplasma pneumoniae encephalitis in children: a case report and literature review. 2024. doi: 10.12201/bmr.202408.00042

  Li Feifan, Zhang shuitang. Impact of Mixed Infections and Antibiotic Resistance Genes on Clinical Features in Children with Mycoplasma pneumoniae Pneumonia. 2024. doi: 10.12201/bmr.202412.00025

  肖岑昕, HUANG Xuri, ZHAO Weidan. The correlation assessment of serum iron in the identification of community-acquired pneumonia in middle-aged and elderly individuals. 2025. doi: 10.12201/bmr.202501.00002

  YE Hongzhou, YUAN Chen. Risk factors of severe pneumonia in children with macrolide-resistant Mycoplasma pneumoniae pneumonia and the construction of prediction model. 2024. doi: 10.12201/bmr.202409.00021

  Zeng Wen-Mei, Zheng Yue, Li Yi-Min. Relationship of Human Neutrophil Peptides with the severity and prognosis of Acute Respiratory Distress Syndrome. 2024. doi: 10.12201/bmr.202410.00060

  Yang ShuJie, Zeng Ying, Yi HaiYing, Huang Jie, Gan Bin, Wei Xian, Tang Yanlin. Observation of the therapeutic effect of less invasive surfactant administration on respiratory distress syndrome in extremely premature infants. 2024. doi: 10.12201/bmr.202410.00018

  wang nan, li lingyan, yang yanhui, gao fangfang, yang mei, qi aixia, chen liping. Analysis of Detection and Epidemiological Characteristics of Respiratory Pathogens in Children in Zibo from 2020 to 2022. 2025. doi: 10.12201/bmr.202504.00019

• ID	Submit time	Number	Download
  1	2025-05-04	bmr.202506.00057V1	Download

• Public  Anonymous  To author only Submit Comments