通讯作者: 成杰, chengjie9655@126.com

DOI：10.12201/bmr.202509.00020

Prognostic Value of systemic immune inflammation index and rSIG shock index in elderly patients with ICH

• 摘要：【摘要】 目的 分析探究全身免疫炎症指数(systemic immune inflammation index,SII ) 联合rSIG休克指数（the Reverse Shock Index Multiplied by Clasgow Coma Scale Score, rSIG）对老年自发性脑出血( intracerebral hemorrhage, ICH)患者预后的预测价值。方法 选取2022年 12月至2024年 12月期间在华北理工大学附属医院神经外科收治的400例老年ICH患者，根据患者90d预后情况分成预后良好组152例和不良248例。比较2组基本资料、格拉斯哥昏迷评分(Glasgow coma scale, GCS)、入院生命体征、实验室检查等临床资料。通过logistic回归分析探讨老年ICH患者预后相关的影响因素，根据受试者工作特征曲线分析SII联合rSIG休克指数对老年ICH患者预后的预测价值。结果 预后不良组收缩压、GCS评分、rSIG休克指数显著低于预后良好组，心率、血小板计数、嗜中性粒细胞、D-二聚体、SII显著高于预后良好组。logistic 回归分析显示，全身免疫炎症指数（OR=1.119,95%CI：1.077~1.164，P=0.000）、rSIG休克指数（OR=0.826,95%CI：0.790~0.865,P=0.000）可准确预测老年ICH患者预后情况。ROC曲线分析显示，SII、rSIG休克指数预测老年ICH患者90d预后情况的曲线下面积（area under curve, AUC）分别为0.763（95%CI：0.715~0.811）、0.821（95%CI：0.776~0.867），SII联合rSIG休克指数预测老年ICH患者90d预后情况的曲线下面积（AUC）为0.859（95%CI：0.823~0.895），敏感度和特异度分别为82.66%、72.37%，两者联合的AUC优于单独SII、rSIG休克指数，且差异有统计学意义，P<0.05。结论 SII联合rSIG休克指数可以预测老年ICH患者90d预后情况。

  关键词： 脑出血；rSIG休克指数；全身免疫炎症指数；预后; ; ; 

   

  Abstract: Objective To explore systemic immune inflammation index(SII)combined with? Reverse Shock Index Multiplied by Clasgow Prognostic value of Coma Scale Score(rSIG))for elderly patients with intracerebral hemorrhage(ICH). Methods A total of 400 elderly ICH patients admitted to the Department of Neurosurgery of the Affiliated Hospital of North China University of Science and Technology from December 2022 to December 2024 were selected and divided into a good prognosis group(152 cases)and a poor prognosis group(248 cases) according to the 90d prognosis. Systolic blood pressure, GCS score and rSIG shock index in the poor prognosis group were significantly lower than those in the good prognosis group, while heart rate, platelet count, neutrophil, D-dimer and SII in the poor prognosis group were significantly higher than those in the good prognosis group. Logistic regression analysis was used to explore the prognostic factors of elderly ICH patients, and the predictive value of systemic immune inflammation index combined with rSIG shock index for elderly ICH patients was analyzed according to the subjects working characteristic curve. Results A total of 400 patients were included, including 152 patients in the good prognosis group and 248 patients in the poor prognosis group. Systolic blood pressure and GCS scores in the poor prognosis group were significantly lower than those in the good prognosis group, while heart rate, platelet count, neutrophil, D-dimer, systemic immune inflammation index and rSIG shock index were significantly higher than those in the good prognosis group. logistic regression analysis showed that the systemic immune inflammation index(OR=1.119,95%CI: 1.077-1.164, P=0.000)and rSIG shock index(OR=0.826,95%CI: 0.790-0.865,P=0.000)can accurately predict the prognosis of elderly ICH patients. ROC curve analysis showed that the area under curve of systemic immune inflammation index and rSIG shock index in predicting the 90d prognosis of elderly ICH patients was 0.763(95%CI: 0.715-0.811) and 0.821(95%CI: 0.776~0.867), the area under the curve of systemic immune inflammation index combined with rSIG shock index to predict the 90d prognosis of elderly ICH patients was 0.859(95%CI: 0.823-0.895), and the sensitivity and specificity were 82.66% and 72.37%, respectively. The combined AUC was significantly better than the systemic immune inflammation index and rSIG shock index alone, and the difference was statistically significant(P<0.05). Conclusion Systemic immune inflammation index combined with rSIG shock index can predict the 90d prognosis of elderly patients with ICH.

  Key words: Cerebral hemorrhage; the Reverse Shock Index Multiplied by Clasgow Coma Scale Score; systemic immune inflammation index; prognosis

  提交时间：2025-09-06

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
• html

• 图表

• 周林. 血清GP73联合预后营养指数对HCC患者TACE术后预后的评估价值. 2024. doi: 10.12201/bmr.202409.00043

  何景梅, 张晓玲, 陈琨. 系统性炎症反应指数、乳酸脱氢酶及谷草转氨酶用于识别成人暴发性心肌炎高危人群的价值分析. 2024. doi: 10.12201/bmr.202410.00070

  马家慧, 王忠. 心力衰竭患者血浆C1q/肿瘤坏死因子相关蛋白6、系统性炎症反应指数水平及临床意义. 2025. doi: 10.12201/bmr.202501.00060

  冀鹏磊, 髙崴崴, 李佳霖, 刘待见, 王昱林. 免疫炎症相关指数与重症肺炎转归相关性分析. 2024. doi: 10.12201/bmr.202409.00062

  王安莉, 王建玲, 张文婷, 罗海波, 文庭孝, 杨飞龙. 基于PMC指数模型的我国老年健康政策量化评价研究. 2024. doi: 10.12201/bmr.202406.00004

  许景芬. 老年TyG指数与两年认知功能变化的纵向分析. 2025. doi: 10.12201/bmr.202506.00062

  钱新阳, 王育民. pSOFA评分联合AGI分级评估脓毒症患儿预后的价值. 2024. doi: 10.12201/bmr.202411.00002

  历颖, 吕丹, 黄岭葳, 何菲. 踝臂指数临床应用的最新研究进展. 2025. doi: 10.12201/bmr.202504.00076

  杨林. 冠状动脉周围脂肪衰减指数联合实验室指标预测急性冠脉综合征的研究. 2024. doi: 10.12201/bmr.202409.00001

  刘慧敏, 童明富. 甘油三酯葡萄糖体质量指数、血浆致动脉粥样硬化指数与胆石症的相关性研究. 2024. doi: 10.12201/bmr.202411.00068

• 序号	提交日期	编号	操作
  2	2025-04-10	bmr.202509.00020V2	下载
  1	2025-04-10	bmr.202509.00020V1	下载

• 公开评论  匿名评论  仅发给作者 提交评论