胡欣. 剖宫产术中寒战风险预测模型及列线图的构建. 2025. biomedRxiv.202501.00053
剖宫产术中寒战风险预测模型及列线图的构建
通讯作者: 胡欣, 375389606@qq.com
DOI:10.12201/bmr.202501.00053
Construction and application evaluation of risk prediction model and nomogram for shivering during cesarean sectio
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摘要:目的 构建剖宫产手术患者术中寒战风险预测模型并验证模型的预测效果。方法 选取温州医科大学附属第二医院2023年1月—2023年4月期间住院行剖宫产手术的患者为研究对象,将发生术中寒战患者(101例)和未发生术中寒战患者(124例)的相关影响因素进行对比,纳入有差异指标进行模型构建,使用AUC、十折交叉验证等指标或手段,对模型进行评价和验证,并绘制预测模型的受试者操作特征曲线及列线图。结果 纳入既往糖尿病史、术前S-AI评分、麻醉方式3个因素构建预测模型。该模型ROC曲线下面积为0.799,P值小于0.001,十折内部交叉验证得出的最大AUC值为0.925,提示模型具有较好的拟合效果及鉴别效度。结论 该模型能较好地预测剖宫产术期间产妇寒战的发生风险,为医护人员及时对高危产妇采取预防性管理措施提供参考。
Abstract: Abstract: Objective To develop and validate a predictive model for the risk of shivering during cesarean section surgery. Methods This study selected women who underwent cesarean sections at our hospital from January 2023 to April 2023 as research subjects. The study compared the relevant influencing factors between patients who experienced intraoperative shivering (n=101) and those who did not (n=124). Various indicators were incorporated into the model construction, and the model was evaluated using metrics such as the Area Under the Curve (AUC) and ten-fold cross-validation. The receiver operating characteristic (ROC) curve and nomogram of the prediction model were also generated. Results Five factors were included in the final prediction model: history of diabetes mellitus, preoperative Simplified Acute Physiology Score (SAPS), anesthesia method, post-anesthesia hypothermia, and intraoperative warming measures. The area under the ROC curve for this model was 0.831 (P < 0.001), with an internal ten-fold cross-validation AUC of up to 0.934, indicating that the model exhibits excellent fitting and discrimination performance. Conclusion The developed model can effectively predict the risk of shivering during cesarean sections, providing valuable guidance for healthcare professionals to implement timely preventive measures for high-risk patients.
Key words: Cesarean section; shivering; Prediction model; S-AI score提交时间:2025-01-19
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序号 提交日期 编号 操作 1 2024-11-25 bmr.202501.00053V1
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