张安邦, 王阿贞, 李响, 时靖宇, 叶涛, 吴远华. 吉兰-巴雷综合征并发重症肌无力1例. 2024. biomedRxiv.202408.00038
吉兰-巴雷综合征并发重症肌无力1例
通讯作者: 吴远华, 957269860@qq.com
DOI:10.12201/bmr.202408.00038
Gillan - the barre syndrome complicated by myasthenia gravis in 1 case
Corresponding author: wuyuanhua, 957269860@qq.com
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摘要:本文介绍了1例47岁男患者,卒中后逐渐出现肢体乏力、麻木。临床医师结合病人临床症状、查体、实验室检查,诊断GBS合并GS,治疗方案采取激素冲击联合胆碱酯酶抑制剂,在治疗中,吞咽困难、饮水呛咳加重,考虑诱发激素抑制免疫反应,遂调整激素用量,加用抗胆碱酯酶制剂,预防胆碱能危象发生,最终患者病情得以有效控制,顺利出院。两病合病,临床极其罕见,附案1例,为临床诊治提供思考。
Abstract: this paper introduces a 47-year-old male patients, gradually developed limb weakness, numbness after stroke. The clinicians combined with the patients clinical symptoms, physical examination, and laboratory examination, diagnosed GBS combined with GS, and the treatment plan was hormone pulse combined with cholinesterase inhibitor. During the treatment, dysphagia and choking during drinking were aggravated, and the hormone was considered to induce the suppression of immune response, so the dose of hormone was adjusted and anti-cholinesterase preparations were added to prevent the occurrence of cholinergic crisis. Finally, the patients condition was effectively controlled and he was discharged smoothly. The combination of the two diseases is extremely rare in clinic. One case is attached, which provides thinking for clinical diagnosis and treatment.
Key words: Myasthenia gravis, Guillain-Barre syndrome, cholinergic crisis,Discussion提交时间:2024-08-20
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序号 提交日期 编号 操作 1 2024-07-15 bmr.202408.00038V1
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